Evaluation Of Uterine Artery Doppler At 11-13+6 Weeks For Prediction Of Pre-Eclampsia-A Descriptive Observational Study

Abstract

Background and objectives Various measurement techniques and impedance indices have been used to evaluate the relationship between uterine artery Doppler velocimetry and adverse pregnancy outcomes. This study was aimed to evaluate bilateral uterine artery Doppler in pregnant women with gestational age between 11+0 to 13+6 weeks in the prediction of preeclampsia and IUGR. Methodology The present one year longitudinal prospective cohort study conducted on 117 pregnant women with gestational age between 11+0 to 13+6 weeks attending antenatal checkup in the Department of Obstetrics and Gynecology, KLES Dr Prabhakar Kore Charitable Hospital and Medical Research Center, Belagavi from January 2016 to December 2016. Results The most common age group was between 21 to 25 years (50.43%) and the mean age was 24.41±4 years. Most of the women were gravida 2 (44.44%). The pulsatality index ranged between 2% to 99%. Majority of the women (89.74%) had normal pulsatality index (<95%) and high (≥95) in 10.26% of the women. Most of the women (57.26%) had vaginal delivery and 42.74% underwent for LSCS. In this study out of 117 women, 30 (25.64%) women had comorbidities. Most common comorbidity was FGR (13.68%) followed by preeclampsia (7.69%). There were five preterm deliveries. Significantly higher number of women with pulsatility index ≥ 95% had preeclampsia (55.56%) (p<0.001) and the sensitivity of PI in prediction of preeclampsia was 55.56% with specificity of 93.52% and there was moderate agreement with Kappa value of 0.426 (95% CI 0.146 to 0.705). No association was found between pulsatality index and FGR (p=0.228). The present study showed positive association between PI of ≥95% with development FGR in pregnancy complicated by preeclampsia (p=0.008). Conclusion and interpretation Based on the findings of this study it may be concluded that, PI of ≥95% is strongly associated with development of preeclampsia and FGR in pregnancy complicated by preeclampsia