A Descriptive Observational Study of Correlation Between Duration of Cohabitation and Adverse Pregnancy Outcomes in Primigravida-Pre-eclampsia And Fetal Growth Restriction at A Tertiary Care Hospital in Belagavi

Abstract

Correlation of cohabitation and adverse pregnancy outcome-Preeclampsia and Fetal growth restriction A descriptive observational study. Authors: Dr. Anusha.jetti, Dr.M.B.Bellad Dept. OBGYN KLEU’s J N Medical College Belagavi -590010 Introduction: Normal pregnancy is associated with tolerance to fetal (foreign) antigens; there is immunological intolerance in pre-eclampsia. This intolerance to foreign antigens (partner) is reduced with repeated maternal exposure to antigens. Methods: Type: Descriptive Observational study Sample: Sample required 320. (Risk of PE 15%with Cohabitation <3 months) Primigravida attending to the teaching hospital attached to KLE University. Time Period:One-year study Duration between marriage and occurrence of pregnancy (the interval <6months and >6months and occurrence of pregnancy) and its association to PE and FGR is studied. Selection Criteria: Inclusion: All primigravidae with singleton pregnancy and with gestational age more than 20weeks withoutknown medical disorder during the study period are enrolled to the Study. Data Analysis: Using appropriate tests with SPSS software.The possible association between duration of cohabitation and other independent variables such as preeclampsia, FGR etc. was found using a chi-square test and Fishers exact test. P value <0.05 was considered statistically significant Results: Incidence of Pre-eclampsia was 11.5% and 4% in less than 6 months and more than 6 monthsrespectively. Fetal Growth restriction of 4% and 3.2% respectively. Conclusion: Shorter the cohabitation (less than 6months before pregnancy) is more associated with preeclampsiaand there was no significant association between FGR and duration of cohabitation.